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SpO2 can be measured by pulse oximetry, an indirect, non-invasive method (meaning it does not involve the introduction of instruments into the body). It works by emitting and then absorbing a light wave passing through blood vessels (or capillaries) in the fingertip. A variation of the light wave passing through the finger will give the value of the SpO2 measurement because the degree of oxygen saturation causes variations in the blood’s colour.